AN UNTARGETED METABOLOMIC ANALYSIS OF LACTICASEIBACILLUS (L.) RHAMNOSUS, LACTOBACILLUS (L.) ACIDOPHILUS, LACTIPLANTIBACILLUS (L.) PLANTARUM AND LIMOSILACTOBACILLUS (L.) REUTERI REVEALS AN UPREGULATED PRODUCTION OF INOSINE FROM L. RHAMNOSUS

An Untargeted Metabolomic Analysis of Lacticaseibacillus (L.) rhamnosus, Lactobacillus (L.) acidophilus, Lactiplantibacillus (L.) plantarum and Limosilactobacillus (L.) reuteri Reveals an Upregulated Production of Inosine from L. rhamnosus

Lactic acid bacteria are considered an inexhaustible source of bioactive compounds; indeed, products from their metabolism are known to have immunomodulatory and anti-inflammatory activity.Recently, we demonstrated that Cell-Free Supernatants (CFS) obtained from Lactobacillus (L.) acidophilus, Lactiplantibacillus (L.) plantarum, Lacticaseibacillus

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Mycobacterium tuberculosis complex lipid virulence factors preserved in the 17,000-year-old skeleton of an extinct bison, Bison antiquus.

Tracing the evolution of ancient diseases depends on the availability and accessibility of suitable biomarkers in archaeological specimens.DNA is potentially information-rich but it depends on a favourable environment for preservation.In the case of the major mycobacterial pathogens, Mycobacterium tuberculosis and Mycobacterium leprae, robust lipid

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